It is good Netiquette to use the out of office reply. Do let co-workers know when your gone and for how long.
Out Of Office Netiquette Work Email
An out of office email reply is an automatic email message. It is sent in response to the receipt of an email message. The out of office email reply message sent is to inform co-workers that the account is not responding to messages.
Work Email Out Of Office
Co-workers need to know when your gone so that they can adjust their work loads accordingly. Use the automatic out of office reply when your gone from the office for more than a half day.
The reply message should include instructions for follow up contact. Additional contacts should be provided. This allows urgent matters to be addressed.
Out Of Office Netiquette
Use the out of office reply when gone because senders may expect a timely response.